Welcome to IMMUNOLOGY2012™
The 99th AAI Annual Meeting!
The Scientific Program at IMMUNOLOGY 2012™ featured cutting-edge developments from scientists at every career stage, including world leaders in immunology presenting their research in plenary lectures and special symposia, award lecture presentations, and major symposia. In addition, more than 550 other AAI members and guests presented their latest findings in over 100 sessions. And over 1,600 poster presenters displayed and discussed their findings throughout the week.
Program By Day | Meeting Abstracts | Photos
AAI President's Address
Leslie J. Berg
University of Massachusetts Medical School, AAI President
Signaling pathways that regulate T cell development and differentiation
AAI President's Symposium
Monday, May 7, 3:30 PM, Ballroom A-C
Signaling through the Tec family kinases; how do these molecules work?
Lawrence E. Samelson, NCI, NIH
TCR-mediated signaling
Pamela L. Schwartzberg, NHGRI, NIH
Understanding the pathogenesis of primary immunodeficiencies using model systems
Mark M. Davis, HHMI, Stanford University
The coming (second) golden age of human immunology
Amy H. Andreotti
Lawrence E. Samelson
Pamela L. Schwartzberg
Mark M. Davis
Saturday, May 5, 5:30 PM, Ballroom A-C
MRC National Institute for Medical Research
Regulation of the immune response in tuberculosis: from mouse models to human disease
Sunday, May 6, 5:30 PM, Ballroom A-C
Brigham and Women's Hospital, Harvard Medical School
Transcriptional regulation of Tregs and Th17 cells
Monday, May 7, 5:30 PM, Ballroom A-C
University of California, Berkeley
Innate natural killer receptors and their ligands: regulation in cancer, infection, inflammatory disease, and steady state
Saturday, May 5, 2012, 8:00 AM - 11:30 AM
Major Symposium A: Developing Immunological Memory to InfectionBallroom B
Patrick C. Wilson, University of Chicago
Susan M. Kaech, Yale University, Transcriptional programs in memory CD8 T cells
Marc K. Jenkins, Center for Immunology, University of Minnesota Medical School Origins of CD4+ memory T cells
Patrick C. Wilson, University of Chicago, Human B cell memory to influenza
Susan Moir, NIAID, NIH, B cell abnormalities in HIV infection: impact on immunologic control of viral replication
Nicole Baumgarth, University of California, Davis, Long-lasting tissue-restricted B cell memory in the respiratory tract
Major Symposium B: Sensing and Signaling in the Innate Immune Response
Ballroom A
Katherine A. Fitzgerald, University of Massachusetts Medical School
Katherine A. Fitzgerald, University of Massachusetts Medical School, AIM2-like receptors: newcomers to the world of inflammasomes
Koichi S. Kobayashi, Dana-Farber Cancer Institute, Regulation of MHC class I and class II pathways by NLR family proteins
Michael Gale, Jr., University of Washington, Immune signaling by RIG-I like receptors
Lynda Stuart, Massachusetts General Hospital, Phagocytosis and innate immunity
Alexander Poltorak, Tufts University, Forward genetic analysis of innate immunity in evolutionarily divergent subspecies of mice
Sunday, May 6, 2012, 8:00 AM - 11:30 AM
Major Symposium C: Innate Lymphoid Cells Back Up the BarriersBallroom B
Hergen Spits, Academic Medical Center, University of Amsterdam
Richard M. Locksley, HHMI, University of California, San Francisco, Innate helper type-2 cells: the missing piece in allergic immunity?
Hergen Spits, Academic Medical Center, University of Amsterdam, Emerging insights in the function and development of human innate lymphoid cells
Daniel J. Cua, Merck Research Laboratories, Regulation of innate lymphoid cells
Wenjun Ouyang, Genentech, Inc., The regulation and function of IL-22 from ILC
Troy D. Randall, University of Alabama, Birmingham, The role of IL-17 and innate lymphoid cells in the development of ectopic follicles
Major Symposium D: Differentiation and Plasticity of Cells of the Monocyte-Macrophage Lineage
Ballroom A
Alberto Mantovani, University of Milan Istituto Clinico Humanitas
Thomas A. Wynn, NIAID, NIH, Macrophages in chronic inflammation and fibrosis
Judith E. Allen, University of Edinburgh, The many faces of Th2-activated macrophages
Stefanie N. Vogel, University of Maryland, Baltimore, Host macrophage responses to infection
Subhra K. Biswas, Singapore Immunology Network (SIgN), Polarized response of monocytes and macrophages in inflammation and cancer
Alberto Mantovani, University of Milan Istituto Clinico Humanitas, Macrophage plasticity and polarization
Monday, May 7, 2012, 8:00 AM - 11:30 AM
Major Symposium E: Building a Functional Immune SystemBallroom B
Ananda W. Goldrath, University of California, San Diego
Stephen T. Smale, University of California, Los Angeles, Analysis of lymphocyte development by targeted mutagenesis of individual zinc fingers of Ikaros
Barbara L. Kee, University of Chicago, Transcriptional mechanisms in natural killer cell development and activation
Derek B. Sant'Angelo, The Child Health Institute, UMDNJ-RWJMS, Transcriptional control of innate T cell development
Ananda W. Goldrath, University of California, San Diego, Transcriptional control of CD8 memory formation
Daniel J. Campbell, Benaroya Research Institute, Control of regulatory T cell homeostasis and function
Major Symposium F: Recent Advances in Lung Immunology: Novel Targets for Lung Disease
Ballroom A
David S. Wilkes, Indiana University School of Medicine
Marsha Wills-Karp, Johns Hopkins Bloomberg School of Public Health, Mechanisms of severe asthma
Anne I. Sperling, University of Chicago, Augmentation of Th2-mediated lung inflammation
Wonder Drake, Vanderbilt University School of Medicine, IL-2 dysregulation drives sarcoidosis disease progression
Dale T. Umetsu, Children's Hospital Boston, Harvard Medical School, Innate lymphoid cells respond to viral infection in the lung
David S. Wilkes, Indiana University School of Medicine, IL-17 and pulmonary fibrogenesis
Tuesday, May 8, 2012, 8:00 AM - 11:30 AM
Major Symposium G: Mucosal Immunity and the MicrobiomeBallroom B
Dana J. Philpott, University of Toronto
Eric G. Pamer, Memorial Sloan-Kettering Cancer Center, Impact of antibiotics on the microbiota and mucosal immunity
Nita H. Salzman, Medical College of Wisconsin, Paneth cell defensins and the regulation of intestinal homeostasis
Richard A. Flavell, HHMI, Yale School of Medicine, Inflammasomes and homeostasis in the intestine and beyond
Tatyana Golovkina, University of Chicago, Commensal bacteria and retroviruses
Peter J. Turnbaugh, Harvard University Center for Systems Biology, A microbial view of nutrition and drug metabolism
Major Symposium H: Stromal Cells for Immune Cell Development and Function
Ballroom A
Jennifer L. Gommerman, University of Toronto
Graham Anderson, MRC Centre for Immune Regulation, University of Birmingham, Lymphostromal interactions in thymus medulla formation
Yousuke Takahama, University of Tokushima, Thymic cortical epithelial cells for T cell repertoire formation
Shannon J. Turley, Dana-Farber Cancer Institute, Harvard Medical School, New roles for lymph node stroma in regulating adaptive immunity
Theresa T. Lu, Hospital for Special Surgery and Weill Cornell Medical College, Regulation of vascular-stromal growth and function
Jennifer L. Gommerman, University of Toronto, Lymphotoxin-dependent stromal cell niches that support immune responses
Annually recognizing immunologists of extraordinary professional achievement and promise, the AAI Career Awards include:
- AAI Lifetime Achievement Award
- AAI Distinguished Service Award
- AAI Excellence in Mentoring Award
- AAI-Life Technologies Meritorious Career Award
- AAI Award for Human Immunology Research
- AAI-BD Biosciences Investigator Award
AAI Lifetime Achievement Award Presentation
University of Massachusetts Medical School, AAI President
HHMI, University of California, San Francisco
AAI Award for Human Immunology Research Presentation and Lecture
University of Massachusetts Medical School, AAI President
Washington University School of Medicine
The complement system and human disease: the consequences of too little or too much
AAI-BD Biosciences Investigator Award Presentation and Lecture
Saturday, May 5, 4:00 PM – 5:00 PM, Ballroom A-C
University of Massachusetts Medical School, AAI President
La Jolla Institute for Allergy and Immunology
Transcriptional regulation of follicular helper CD4 T (Tfh)
cell differentiation
AAI-Life Technologies Meritorious Career Award Presentation and Lecture
Sunday, May 6, 4:00 PM – 5:00 PM, Ballroom A-C
University of Massachusetts Medical School, AAI President
HHMI, Yale University School of Medicine
Molecular and cellular mechanisms that regulate
antigen processing
AAI Distinguished Service Award Presentations
For outstanding service to AAI and the immunology community as Director
of the AAI High School Teachers Summer Research Program, 2007 - 2012
William R. Green, Ph.D., Dartmouth Medical School
For outstanding service to AAI as member and Chair of the AAI Committee
on Public Affairs, 2004 - 2009
John R. Schreiber, M.D., M.P.H., Tufts University School of Medicine
For outstanding service to AAI as member and Chair of the AAI Committee
on Public Affairs, 2005 - 2011
Brian A. Cobb, Ph.D.
William R. Green, Ph.D.
John R. Schreiber, M.D., M.P.H.
AAI Excellence in Mentoring Award Presentation
University of Massachusetts Medical School, AAI President
Emory University School of Medicine
In addition to Career Awards, AAI annually provides more than 500 AAI meeting travel awards and grants to recognize the promise and bolster the professional development of early- and mid-career investigators, including underrepresented minority scientists and trainees.
- AAI Early Career Faculty Travel Grants
- AAI Minority Scientist Travel Awards
- AAI Trainee Abstract Awards
- AAI-Life Technologies Trainee Achievement Awards
- Chambers-eBioscience Memorial Award
- Lustgarten-eBioscience Memorial Award
- Pfizer-Showell Travel Award
- AAI Laboratory Travel Grants
For information on all AAI Awards, visit www.aai.org/Awards.
AAI Clinical Immunology Committee Symposium
Friday, May 4, 2:00 PM - 4:00 PM, Room 302
Barry R. Bloom, Harvard School of Public Health
Cornelia L. Trimble, Johns Hopkins University School of Medicine, Therapeutic targets in preinvasive HPV disease
Barry R. Bloom, Harvard School of Public Health, The challenge of TB vaccines
David Baltimore, California Institute of Technology, Vectored ImmunoProphylaxis: engineering the immune system
AAI Committee on Public Affairs
Monday, May 7, 4:00 PM – 5:00 PM, Room 313
- American Academy of Pediatrics
- Asthma and Allergy Foundation of America
- Lymphatic Research Foundation
- Society for Women's Health Research
- ZERO – The Project to End Prostate Cancer
Saturday, May 5, 11:30 AM – 1:00 PM, Room 309
Daniel Rotrosen, Director, Division of Allergy, Immunology, and Transplantation, NIAID, NIH, The role of NIAID in peer review and grant funding
Elizabeth J. Kovacs, Loyola University Chicago, Chair, AAI Subcommittee on Peer Review and Grant Submission, Grant applicants and reviewers: questions and concerns
AAI Education Committee
Monday, May 7, 12:30 PM – 2:30 PM, Room 208
Jay K. Kolls, Professor, University of Pittsburgh School of Medicine, Commercializing your research: are you ready for an SBIR/STTR grant?
Lisa Kurek, Managing Partner, Biotechnology Business Consultants, Commercialization: it is never too early to start
Thomas M. Aune, Professor, Vanderbilt University Medical Center, Utilizing small business partnerships to advance applied research
Careers in Biotech: Panel Discussion and Networking Reception
Monday, May 7, 6:30 PM – 8:00 PM, Room 302
Andy Kokaji, Senior Scientist, STEMCELL Technologies, Inc.
Chris Schwab, Senior Medical Science Liaison, Human Genome Sciences, Inc.
Olivia Schneider, Chief Scientific Officer, Shenandoah Biotechnology, Inc.
Nurturing the Quest for Science in the Next Generation
Saturday, May 5, 9:00 AM - 12:00 PM, Room 206
Lyndonia Pascal, 2011-2012 AAI HST Program Participant, Palm Beach Lakes Community High School, West Palm Beach, FL, The immune system and the mechanisms of cell proliferation: an introduction to cancer and the IDO pathway
Ann Brokaw, Former AAI HST Program Participant and 2008 Presidential Award for Excellence in Mathematics and Science Teaching Recipient, Rocky River High School, Rocky River, OH, Strengthening immunology and science education in high schools
Kara Lukin, Instructor and Coordinator of the Summer Research Program for High School Educators, National Jewish Health, Easy educational outreach that scientists can perform in one hour
Brooke Jude, Director, Citizen Science Program, Bard College, The Citizen Science Program at Bard College: improving science literacy in college freshmen
Judith A. Owen, Professor, Haverford College, Enhancing undergraduate science and research programs through an upper-level, independent laboratory model
AAI Education Committee & AAI Committee on the Status of Women
Generously sponsored by BD Biosciences, Inc.
Sunday, May 6, 12:30 PM – 2:30 PM, Sheraton Boston Hotel, Republic Ballroom
Make an effort! A path to a rewarding life in science
Discussion topics and table leaders:
- Research Careers in Academia
Table Leaders: Anne I. Sperling, University of Chicago; Vijay K. Kuchroo, Harvard Medical School; Dario A. A. Vignali, St. Jude Children's Research Hospital - Mentoring Effectively
Table Leaders: Scheherazade Sadegh-Nasseri, Johns Hopkins University Medical School - Networking Skills
Table Leader: Monica Mann, EMD Serono, Inc. - Career and Family: time management/family leave/professional couples
Table Leader: Patricia Fitzgerald-Bocarsly, UMDNJ - Careers in Biotech and Industry: moving from academia to industry and vice versa;
Table Leaders: Mary E. Keir, Genentech, Inc.; Daniel J. Cua, Merck Research Laboratories; Robert Balderas, BD Biosciences, Inc. - Careers at Governmental Agencies (FDA/NIH/USDA/CDC)
Table Leaders: A. Andrew Hurwitz, NCI/NIH; Pamela L. Schwartzberg, NHGRI/NIH; Thandi M. Onami, NIH/NIAID - Graduate Student to Postdoc: finding a postdoc, interviewing
Table Leaders: Michele A. Parent, University of Delaware; Terrence L. Geiger, St. Jude Children's Hospital - New PI: attracting students and postdocs, preparing for tenure
Table Leaders: Janis K. Burkhardt, University of Pennsylvania School of Medicine; Patricia Cortes, Mount Sinai School of Medicine - Non-research Careers: focus for 2012 — careers in intellectual property/patent law; technology transfer
Table Leader: Alexander Swirnoff, Pfizer, Inc. - Postdoc to PI: finding a position, interviewing, negotiating, lab start-up
Table Leader: Shannon J. Turley, Dana Farber Cancer Institute, Harvard Medical School - Translational Research: careers that bridge basic and clinical research
Table Leaders: Arthur Tzianabos, Shire Human Genetic Therapies; Charlotte Cunningham-Rundles, Mount Sinai School of Medicine - Undergraduate Institutions: teaching, doing research
Table Leader: Sharon A. Stranford, Mt. Holyoke College
AAI Membership Committee
Friday, May 4, 4:00 PM – 4:45 PM
AAI wishes to welcome new Regular and Trainee members joining AAI for the first time. AAI President Leslie Berg and other AAI leaders look forward to meeting you personally. Please join us with your invitation in hand for light refreshments and casual conversation. Event by invitation only.
AAI Minority Affairs Committee
Saturday, May 5, 11:45 AM – 1:15 PM, Room 313
Don't miss this opportunity to meet one-on-one with accomplished, senior minority immunologists to hear how they have handled the career challenges you now face. Learn what they believe will work for you today.
- Grad Student: finding a mentor; taking aim at postdoc training
Table Leaders: Joseph Larkin, III, University of Florida; Tonya J. Webb, University of Maryland, Baltimore; Anthony Quinn, University of Toledo - Postdoc: finding a mentor; taking aim at a faculty position
Table Leaders: José R. Conejo-Garcia, The Wistar Institute; Gregory B. Carey, University of Maryland, Baltimore; Margaret S. Bynoe, Cornell University College of Veterinary Medicine - Junior Faculty: preparing for promotion and tenure
Table Leaders: Adriana T. Larregina, University of Pittsburgh School of medicine; Avery August, Cornell University; Prosper N. Boyaka, Ohio State University - Academia or Industry: how to decide (or switch sides)
Table Leaders: Rebecca McHugh, Miltenyi Biotec Inc.; Jonathan A. Deane, Genomics Institute of the Novartis Research Foundation; Cherié L. Butts, Biogen Idec - Government Agency Careers: CDC, FDA, NIH
Table Leaders: Thandi M. Onami, NIAID, NIH; Charles E. Egwuagu, NEI, NIH - Non-Research Careers: science journalism, patent law, biomedical entrepreneurship
Table Leaders: John Emrich, AAI; TBA
Monday, May 7, 1:00 PM – 2:00 PM, Room 310
Chair, AAI Minority Affairs Committee
AAI Publications Committee Session
Saturday, May 5, 12:30 PM - 2:30 PM, Room 310
Understanding the process of preparing and reviewing a manuscript can improve the outcome for all involved. In this session sponsored by the AAI Publications Committee, experienced editors, reviewers, and authors will provide valuable insights by addressing questions such as:
- How can a reviewer help improve the process of scientific publication?
- What do journal editors look for from reviewers of manuscripts?
- When writing a manuscript, what steps can an author take to enhance its impact on editors, reviewers and, if accepted for publication, on readers?
- How can authors enhance the presentation of data in figures?
- What are recommended practices for responding to reviewers' comments?
Kaylene J. Kenyon, AAI/The Journal of Immunology
Juan Carlos Zúñiga-Pflücker, University of Toronto, The art of writing a manuscript
Herman F. Staats, Duke University, Returned for revision: responding to reviewers' comments
Jeremy M. Boss, Emory University, It's all in the figures: preparing figures and other ethical matters
AAI Veterinary Immunology Committee & American Association of Veterinary Immunologists (AAVI) Joint Symposium
Monday, May 7, 10:15 AM – 12:15 PM, Room 206
Paul M. Coussens, Michigan State University
Sabra L. Klein, Johns Hopkins Bloomberg School of Public Health, Zoonotic pathogen-host interactions: sex determines the outcome of infection
Robert A. Heinzen, Rocky Mountain Laboratories, NIAID, NIH, Subversion of macrophage function by the Q fever agent, Coxiella burnetii
Mary Pantin-Jackwood, Southeast Poultry Research Laboratory, USDA, Current situation of avian influenza with emphasis on pathobiology, epidemiology, and control
National Institute of Allergy and Infectious Diseases (NIAID) Symposium
Sunday, May 6, 3:30 PM – 5:30 PM, Room 304
Michael P. Cancro, University of Pennsylvania School of Medicine
Susan Zolla-Pazner, New York University Langone School of Medicine, Conserved features of variable regions: important targets of neutralizing antibodies
Shiv Pillai, Massachusetts General Hospital, Harvard Medical School, SIAE suppresses promiscuous T-B collaboration and germinal center formation
James Kobie, University of Rochester Medical Center, The cellular origins of protective antibody responses to HIV
National Institute on Aging (NIA) Symposium
Saturday, May 5, 3:30 PM – 5:30 PM, Room 306
Carlos J. Orihuela, University of Texas Health Science Center at San Antonio, Cellular senescence as a source of chronic inflammation in the lungs and mechanism for enhanced susceptibility to bacterial pneumonia
Daniel R. Goldstein, Yale School of Medicine, Dysregulated inflammation, aging, and viral infections
Susan L. Swain, University of Massachusetts Medical School, Can we overcome the defects of aged CD4+ naive T cells?
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Symposium
Monday, May 7, 10:15 AM – 12:15 PM, Room 306
Susana Serrate-Sztein, NIAMS, NIH
Anne Davidson, Feinstein Institute for Medical Research, Renal macrophages in lupus nephritis – friend or foe?
Vicki Rubin Kelley, Brigham and Women's Hospital, The "Big Mac" theory of lupus
Kevin D. Cooper, Case Western Reserve University, Monocytes/macrophages in psoriasis
National Institute of Environmental Health Sciences (NIEHS) Symposium
Monday, May 7, 12:30 PM – 2:30 PM, Room 306
B. Paige Lawrence, University of Rochester School of Medicine and Dentistry
Jean C. Pfau, Idaho State University, Silica, asbestos, and systemic autoimmune disease
David H. Sherr, Boston University School of Public Health, Environmental chemicals as probes of immune system development
Frederick W. Miller, NIEHS, NIH, An overview of environmental risk factors for autoimmune diseases: where we stand in 2012
American Association of Pharmaceutical Scientists (AAPS) Symposium
Sunday, May 6, 8:00 AM – 10:00 AM, Room 309
Bonnie Rup, Pfizer, Inc.
Bonnie Rup, Pfizer, Inc., The problem of unwanted immunogenicity in biotherapeutic treatment: causes, consequences, and opportunities
Terry Goletz, Amgen, Inc., Predicting immunogenicity: tools and approaches for understanding the mechanisms underlying an immune response
Susan Richards, Genzyme, a Sanofi Company, Immune mitigation and tolerance induction to therapeutic proteins
American Association of Veterinary Immunologists (AAVI) & AAI Veterinary Immunology Committee Joint Symposium
Monday, May 7, 10:15 AM – 12:15 PM, Room 206
Paul M. Coussens, Michigan State University
Sabra L. Klein, Johns Hopkins Bloomberg School of Public Health, Zoonotic pathogen-host interactions: sex determines the outcome of infection
Robert A. Heinzen, Rocky Mountain Laboratories, NIAID, NIH, Subversion of macrophage function by the Q fever agent, Coxiella burnetii
Mary Pantin-Jackwood, Southeast Poultry Research Laboratory, USDA, Current situation of avian influenza with emphasis on pathobiology, epidemiology, and control
American Society for Blood and Marrow Transplantation (ASBMT) Symposium
Saturday, May 5, 8:00 AM – 10:00 AM, Room 306
Mary J. Laughlin, University of Virginia, Measurements of immune recovery after cord blood transplantation
Ephraim J. Fuchs, Johns Hopkins University, Measurements of immune recovery after haploidentical transplantation
Robert S. Negrin, Stanford University, Influence of laboratory measures of immune recovery on clinical outcomes
American Society of Bone and Mineral Research (ASBMR) Symposium
Saturday, May 5, 10:15 AM – 12:15 PM, Room 306
Joseph Lorenzo, University of Connecticut Health Center
Mary Beth Humphrey, University of Oklahoma Health Science Center, Negative regulatory mechanisms of ITAM signaling in osteoclasts
Edward M. Schwarz, University of Rochester, Osteoimmunology of arthritis flare
Louis C. Gerstenfeld, Boston University School of Medicine, Multiple stages of immune cell function during fracture healing
American Society of Transplantation (AST) Symposium
Monday, May 7, 12:30 PM – 2:30 PM, Room 304
Jonathan S. Maltzman, University of Pennsylvania
Arlene H. Sharpe, Harvard Medical School, Immunomodulation by co-inhibitory receptors
Agnes M. Azimzadeh, University of Maryland School of Medicine, Selective blockade of CD28 in organ transplantation
Christian P. Larsen, Emory University Hospital, Bringing costimulatory blockade into the clinic
British Society for Immunology (BSI) Symposium
Sunday, May 6, 10:15 AM – 12:15 PM, Room 306
Gavin R. Screaton, Imperial College London, Immunopathology in dengue virus infection
Tracy Hussell, Imperial College London, Immune pathology in lung viral infection: innate or adaptive?
Paul A. H. Moss, University of Birmingham, The biology and therapeutic management of the immune response to human cytomegalovirus in health and disease
Canadian Society for Immunology (CSI) Symposium
Saturday, May 5, 12:30 PM – 2:30 PM, Room 306
Alberto Martin, University of Toronto
Aaron J. Marshall, University of Manitoba, PI3-kinase pathway in B cell-associated pathologies
Julie P. Deans, University of Calgary, CD20 and related proteins in B cell regulation
Alberto Martin, University of Toronto, Antibody diversification mechanisms and their role in humoral immunity
Randy D. Gascoyne, University of British Columbia, Genetic mechanisms underlying immune privilege in lymphoid cancers
Chinese Society of Immunology (ChSI) Symposium
Monday, May 7, 10:15 AM – 12:15 PM, Room 310
Olivera J. Finn, University of Pittsburgh
Zhigang Tian, China University of Science and Technology, Hefei, NK cell pathobiology and immunotherapy of hepatitis and liver cancer patients
Xueguang Zhang, Suzhou University School of Medicine, Co-stimulators and co-inhibitors in cancer patients
Haiyan Liu, Suzhou University School of Life Sciences, New approaches to improve BMT
Yuzhang Wu, Third Military Medical University, Chongqing, Clinical trials of a new type of HBV therapeutic vaccine
German Society for Immunology (DGfI) Symposium
Sunday, May 6, 12:30 PM – 2:30 PM, Room 306
Hans-Martin Jäck, University of Erlangen
Jürgen Wienands, University of Göttingen, Activation signals for naive and class-switched memory B cells
Andreas Radbruch, Deutsches Rheuma-Forschungszentrum Berlin, Memory plasma cells
Hans-Martin Jäck, University of Erlangen, miRNA-dependent control of B cell differentiation
Claudia Berek, Deutsches Rheuma-Forschungszentrum Berlin, How plasma cells survive
International Society for Interferon and Cytokine Research (ISICR) Symposium
Saturday, May 5, 12:30 PM – 2:30 PM, Room 304
Stefania Gallucci, Temple University
Ana M. Gamero, Temple University, STAT2 in the inflammatory and antiviral response
Stefania Gallucci, Temple University, Regulation of type I interferon in murine lupus
Andrew A. Welcher, Amgen, Inc., Demonstration of biological impact of IFN-γ inhibition in SLE subjects treated with AMG 811
International Society of Neuroimmunology (ISNI) Symposium
Saturday, May 5, 8:00 AM – 10:00 AM, Room 310
Tomas Olsson, Karolinska Institute
Tomas Olsson, Karolinska Institute, Gene-environment interactions in neuroinflammation
Philip L. De Jager, Harvard Medical School, The genetic architecture of multiple sclerosis
Chris Cotsapas, Yale School of Medicine, Common genetic variants of autoimmune disease
Society for Natural Immunity (SNI) Symposium
Sunday, May 6, 12:30 PM – 2:30 PM, Room 306
Hans-Gustaf Ljunggren, Karolinska Institute
Hans-Gustaf Ljunggren, Karolinska Institute, The human NK cell repertoire and its modulation by viral infections
Marcus Altfeld, Ragon Institute of MGH, MIT, and Harvard, NK cell responses against HIV-1
Kathleen L. Collins, University of Michigan, The antiviral factor APOBEC3G enhances recognition of HIV-infected cells by NK cells
Through workshops, roundtables, and one-on-one counseling, IMMUNOLOGY 2012™ provides critical career development programs.
Career sessions and services this year include:
- Academics and SBIR/STTR Grants: Seeking Opportunities
- Careers in Biotech Panel Discussion and Networking Reception
- Careers in Science Lecture and Networking Roundtables (2)
- How to Convert Your CV into a Resumé (followed by one-on-one counseling)
- Interviewing for a Job
- Secrets for a Successful Postdoctoral Fellowship
- Writing and Reviewing Manuscripts: Two Sides of the Same Coin
Session Descriptions
Academics and SBIR/STTR Grants: Seeking OpportunitiesJay K. Kolls, Professor, University of Pittsburgh School of Medicine, Commercializing your research: are you ready for an SBIR/STTR grant?
Lisa Kurek, Managing Partner, Biotechnology Business Consultants, Commercialization: it is never too early to start
Thomas M. Aune, Professor, Vanderbilt University Medical Center, Utilizing small business partnerships to advance applied research
Andy Kokaji, Senior Scientist, STEMCELL Technologies, Inc.
Chris Schwab, Senior Medical Science Liaison, Human Genome Sciences, Inc.
Olivia Schneider, Chief Scientific Officer, Shenandoah Biotechnology, Inc.
Saturday, May 5, 11:45 AM – 1:15 PM, Room 313
Don't miss this opportunity to meet one-on-one with accomplished, senior minority immunologists to hear how they have handled the career challenges you now face. Learn what they believe will work for you today.
- Grad Student: finding a mentor; taking aim at postdoc training
Table Leaders: Joseph Larkin, III, University of Florida; Tonya J. Webb, University of Maryland, Baltimore; Anthony Quinn, University of Toledo - Postdoc: finding a mentor; taking aim at a faculty position
Table Leaders: José R. Conejo-Garcia, The Wistar Institute; Prosper N. Boyaka, Ohio State University; Gregory B. Carey, University of Maryland, Baltimore; Margaret S. Bynoe, Cornell University College of Veterinary Medicine - Junior Faculty: preparing for promotion and tenure
Table Leaders: Adriana T. Larregina, University of Pittsburgh School of medicine; Avery August, Cornell University; Gregory B. Carey, University of Maryland, Baltimore - Academia or Industry: how to decide (or switch sides)
Table Leaders:Rebecca McHugh, Miltenyi Biotec Inc.; Jonathan A. Deane, Genomics Institute of the Novartis Research Foundation; Cherié L. Butts, Biogen Idec - Government Agency Careers: CDC, FDA, NIH, USDA
Table Leaders: Thandi M. Onami, NIAID, NIH; Charles E. Egwuagu, NEI, NIH - Non-Research Careers: science journalism, patent law, biomedical entrepreneurship
Table Leaders: John Emrich, AAI; TBA
Generously sponsored by BD Biosciences, Inc.
Sunday, May 6, 12:30 PM – 2:30 PM, Sheraton Boston Hotel, Republic Ballroom
Make an effort! A path to a rewarding life in science
Discussion topics and table leaders):
- Research Careers in Academia
Table Leaders: Anne I. Sperling, University of Chicago; Vijay K. Kuchroo, Harvard Medical School; Dario A. A. Vignali, St. Jude Children's Research Hospital - Mentoring Effectively
Table Leaders: Scheherazade Sadegh-Nasseri, Johns Hopkins University Medical School - Networking Skills
Table Leader: Monica Mann, EMD Serono, Inc. - Career and Family: time management/family leave/professional couples
Table Leader: Patricia Fitzgerald-Bocarsly, UMDNJ - Careers in Biotech and Industry: moving from academia to industry and vice versa;
Table Leaders: Mary E. Keir, Genentech, Inc.; Daniel J. Cua, Merck Research Laboratories; Representative of BD Biosciences, Inc. - Careers at Governmental Agencies (FDA/NIH/USDA/CDC)
Table Leaders: A. Andrew Hurwitz, NCI/NIH; Pamela L. Schwartzberg, NHGRI/NIH; Thandi M. Onami, NIH/NIAID - Graduate Student to Postdoc: finding a postdoc, interviewing
Table Leaders: Michele A. Parent, University of Delaware; Terrence L. Geiger, St. Jude Children's Hospital - New PI: attracting students and postdocs, preparing for tenure
Table Leaders: Janis K. Burkhardt, University of Pennsylvania School of Medicine; Patricia Cortes, Mount Sinai School of Medicine - Non-research Careers: focus for 2012 — careers in intellectual property/patent law; technology transfer
Table Leader: Alexander Swirnoff, Pfizer, Inc. - Postdoc to PI: finding a position, interviewing, negotiating, lab start-up
Table Leader: Shannon J. Turley, Dana-Farber Cancer Institute, Harvard Medical School - Translational Research: careers that bridge basic and clinical research
Table Leaders: Arthur Tzianabos, Shire Human Genetic Therapies; Charlotte Cunningham-Rundles, Mount Sinai School of Medicine - Undergraduate Institutions: teaching, doing research
Table Leader: Sharon A. Stranford, Mt. Holyoke College
Small breakout sessions for individual consulting will follow from 1:45 PM to 3:45 PM. Bring your CV!
Understanding the process of preparing and reviewing a manuscript can improve the outcome for all involved. In this session sponsored by the AAI Publications Committee, experienced editors, reviewers, and authors will provide valuable insights by addressing questions such as:
- How can a reviewer help improve the process of scientific publication?
- What do journal editors look for from reviewers of manuscripts?
- When writing a manuscript, what steps can an author take to enhance its impact on editors, reviewers and, if accepted for publication, on readers?
- How can authors enhance the presentation of data in figures?
- What are recommended practices for responding to reviewers' comments?
Kaylene J. Kenyon, AAI/The Journal of Immunology
Juan Carlos Zúñiga-Pflücker, University of Toronto, The art of writing a manuscript
Herman F. Staats, Duke University, Returned for revision: responding to reviewers' comments
Jeremy M. Boss, Emory University, It's all in the figures: preparing figures and other ethical matters
Monday, May 7, 11:30 AM – 1:00 PM, Room 309
This session will include the annual report to AAI members on AAI and The Journal of Immunology business affairs and will feature select 2012 AAI awards presentations and acknowledgements. Lunch will be provided.
Presentations and acknowledgements to include:
- Distinguished Service Awards
- Lustgarten-eBioscience Memorial Award
- Pfizer-Showell Travel Award
- Cynthia Chambers Memorial-eBioscience Junior Faculty Award
- AAI-Life Technologies Trainee Achievement Awards
- AAI Early Career Faculty Travel Grant
- AAI Minority Scientist Travel Awards
- AAI Trainee Abstract Awards
- AAI Laboratory Travel Grants
View Immunology 2012™ Block Symposia Schedule
Block Symposia - Selected abstracts are programmed into oral sessions called Block Symposia. Each Block Symposium is made up of approximately 8 selected abstracts. There are 69 Block Symposia programmed for this annual meeting.
Posters - The most interactive part of the meeting! Discuss data and research issues firsthand with authors at the Poster Sessions. Posters will be displayed Saturday through Monday in the Hynes Convention Center Auditorium and Exhibit Hall C-D from 9:30 AM – 4:30 PM.
Dedicated Daily Poster Presentation Hour from 2:30 PM to 3:30 PM! No concurrent symposia, presentations, or other sessions will be held during the poster presentations at this time.
Accepted posters may be displayed for the duration of the meeting! Authors are encouraged to leave their posters up throughout IMMUNOLOGY 2012™.
IMMUNOLOGY 2012™ Opening Night Welcome Reception
Generously sponsored by eBioscience, Inc.
6:00 PM – 8:00 PM
Friday, May 4, 2012
Boylston Hallway, Hynes Convention Center
Come directly from the President's Address into the majestic glass logia of the Hynes Convention Center to seek out old friends and make new acquaintances at the Opening Night Welcome Reception. The reception is generously supported by eBioscience to welcome you and wish you a pleasurable, productive week.
President's Service Appreciation Reception
Generously sponsored by BioLegend
7:00 PM – 9:30 PM
Saturday, May 5, 2012
At this important event, AAI leadership honors the association's dedicated member volunteers – the committee members, editors, mentors, instructors, and others – who work on the membership's behalf throughout the year by giving generously of their time in support of the AAI mission. Open to 2011-2012 AAI volunteers, by invitation only.
IMMUNOLOGY 2012™ Gala "Casino Night in Back Bay"
Generously sponsored by BioLegend
7:00 PM – 10:00 PM
Sunday, May 6, 2012
Sheraton Boston Hotel, Grand Ballroom
Everyone's a winner at Casino Night in the Back Bay! There, you and your most circumspect colleagues can throw caution to the winds and revel in one another's encounters with Lady Luck. It's your risk-free opportunity to "go for broke" and hone your gambling skills, moving from table to table for Black Jack, Roulette, Texas Hold 'Em, Craps, Slots, and more. When your chips are gone, continue the fun at the photo booths or on the karaoke stage performing your favorite song!
New Member Reception
Friday, May 4, 4:00 PM – 4:45 PM
AAI wishes to welcome new Regular and Trainee members joining AAI for the first time. AAI President Leslie Berg and other AAI leaders look forward to meeting you personally. Please join us for light refreshments and casual conversation. Event by invitation only.
Exhibitor Workshops - Take advantage of the opportunity provided by the Exhibitor Workshops to explore exhibitors' latest technologies, products, and services. For a list of 2012 exhibitor workshops, see pages 47-48 of the Program.
Workshops are planned and conducted by exhibitors; the listing of these workshops does not constitute endorsement of any products or services by AAI.
Product Showcases - Be sure to catch the presentations and demonstrations of exhibitors' new products. Sessions are scheduled in 15-minute intervals on the Exhibit Hall Stage. For a list of 2012 product showcase, see page 49 of the Program.
Presentations are planned and conducted by exhibitors; the listing of these presentations does not constitute endorsement of any products or services by AAI.